Step 1: Concept
Proton Pump Inhibitors (PPIs) are drugs that provide potent and long-lasting reduction of gastric acid production.
Step 2: Meaning
They work by irreversibly blocking the enzyme system $H^+/K^+$ ATPase (the proton pump) in the gastric parietal cells.
Step 3: Analysis
Ranitidine and Famotidine are $H_2$-receptor antagonists. Sucralfate is a mucosal protective agent. Omeprazole is the prototype drug of the PPI class.
Step 4: Conclusion
Therefore, Omeprazole is the correct example of a proton pump inhibitor.
Final Answer: (B)