Question:

In the chromosomes, DNA is associated with histone and non-histone proteins. This was reported in 1974 by -----------------.

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Recall who described the nucleosome as the repeating unit of chromatin in 1974.
Updated On: Nov 12, 2026
  • F.H.C. Crick
  • F. Miescher
  • F. Griffith
  • R. Kornberg
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The Correct Option is D

Solution and Explanation

Step 1: Understanding the Concept
In chromosomes, DNA wraps around a core of histone proteins and non-histone proteins are also attached.

Step 2: Who reported it
Roger Kornberg in 1974 described chromatin as a chain of repeating units called nucleosomes.

Step 3: Why the other options fail
Crick is known for the double-helix model (1953), Miescher for discovering nuclein (1869) and Griffith for the transformation experiment (1928).

Final Answer:
R. Kornberg reported this in 1974. \[ \boxed{\text{(D) }\text{R. Kornberg}} \]
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