Question

In glycolysis, which enzyme requires \(\text{Zn}^{2+}\) as cofactor?

• A. Hexokinase
• B. Phosphofructokinase
• C. Aldolase
• D. Glyceraldehyde phosphate dehydrogenase

Hint:

Think of the enzyme that cleaves the six carbon sugar bisphosphate into two trioses.

Answer 1

The Correct Option is C

Step 1: Understanding the Concept
Many glycolytic enzymes need metal ions or coenzymes to work.

Step 2: Check the enzymes
Hexokinase and phosphofructokinase transfer phosphate from ATP and need magnesium.\nGlyceraldehyde phosphate dehydrogenase works with the coenzyme NAD.

Step 3: Conclusion
Aldolase splits fructose-1,6-bisphosphate into PGAL and DHAP and is listed with \(\text{Zn}^{2+}\) as its metal cofactor.

Final Answer:
Aldolase requires zinc as cofactor. \[ \boxed{\text{(C) }\text{Aldolase}} \]