Question:
How many $CO_2$ molecules are released after oxidation of one acetyl CoA in Krebs cycle?
How many $CO_2$ molecules are released after oxidation of one acetyl CoA in Krebs cycle?
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Krebs cycle output (per acetyl CoA): 2 CO$_2$, 3 NADH, 1 FADH$_2$, 1 ATP.
Updated On: May 4, 2026
- One
- Two
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The Correct Option is B
Solution and Explanation
Concept:
The Krebs cycle (TCA cycle) oxidizes one molecule of acetyl CoA completely to carbon dioxide.
Step 1: Understand decarboxylation steps. During one turn of Krebs cycle:
• Isocitrate $\rightarrow$ $\alpha$-ketoglutarate → releases 1 $CO_2$
• $\alpha$-ketoglutarate $\rightarrow$ Succinyl CoA → releases 1 $CO_2$
Step 2: Total CO$_2$ released. \[ \text{Total CO}_2 = 2 \]
Step 3: Conclusion. \[ \text{Two molecules of CO}_2 \text{ are released per acetyl CoA} \]
The Krebs cycle (TCA cycle) oxidizes one molecule of acetyl CoA completely to carbon dioxide.
Step 1: Understand decarboxylation steps. During one turn of Krebs cycle:
• Isocitrate $\rightarrow$ $\alpha$-ketoglutarate → releases 1 $CO_2$
• $\alpha$-ketoglutarate $\rightarrow$ Succinyl CoA → releases 1 $CO_2$
Step 2: Total CO$_2$ released. \[ \text{Total CO}_2 = 2 \]
Step 3: Conclusion. \[ \text{Two molecules of CO}_2 \text{ are released per acetyl CoA} \]
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