Question:
Hemolytic anemia and methemoglobinemia are adverse effect of which drug
Hemolytic anemia and methemoglobinemia are adverse effect of which drug
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Dapsone = "Double Blood" trouble (Anemia and Methemoglobinemia).
Updated On: May 15, 2026
- Dapsone
- Clofazimine
- Rifampicin
- Ethionamide
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Verified By Collegedunia
The Correct Option is A
Solution and Explanation
Step 1: Concept
Adverse drug reactions involving blood cells are common with certain sulfur-containing compounds.
Step 2: Meaning
Hemolytic anemia involves the destruction of red blood cells, and methemoglobinemia is a condition where iron in hemoglobin is oxidized, reducing oxygen transport.
Step 3: Analysis
Dapsone, used for leprosy and dermatitis herpetiformis, is well-known for causing oxidant stress on red blood cells, leading to both hemolysis and methemoglobinemia.
Step 4: Conclusion
These hematological toxicities are characteristic dose-limiting side effects of Dapsone. Final Answer: (a)
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