Question

Which of the following is not a sulphonamide derivative?

• A. Rizatriptan
• B. Sumatriptan
• C. Almotriptan
• D. Naratriptan

Answer 1

The Correct Option is A

The question asks which of the following is not a sulphonamide derivative. Let's analyze each option to identify the correct answer.

1. Rizatriptan: Rizatriptan is a medication used to treat migraine headaches. It belongs to a class of drugs known as triptans, which are serotonin receptor agonists. Rizatriptan does not contain a sulfonamide group.
2. Sumatriptan: Like Rizatriptan, Sumatriptan is also a triptan, used for treating migraines. It does contain a sulphonamide moiety. Hence, it is a sulphonamide derivative.
3. Almotriptan: Almotriptan is another triptan used for migraine treatment. It has a sulphonamide group in its structure, making it a sulphonamide derivative.
4. Naratriptan: Naratriptan is used in migraine management and also contains a sulphonamide group, classifying it as a sulphonamide derivative.

Based on the above information, Rizatriptan is not a sulphonamide derivative. It is distinct from the other given options as it does not contain the sulphonamide functional group. Thus, the correct answer is Rizatriptan.