Question:
H and L (lymphocytic and histiocytic) cells are seen in which type of Hodgkin lymphoma?
H and L (lymphocytic and histiocytic) cells are seen in which type of Hodgkin lymphoma?
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Popcorn (L&H) cells instead of Reed-Sternberg cells point to which subtype?
Updated On: Jun 24, 2026
- Mixed cellularity Hodgkin
- Lymphocyte depleted
- Lymphocyte predominance
- Nodular sclerosis
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The Correct Option is C
Solution and Explanation
Step 1: Hodgkin lymphoma is divided into classical Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL). Step 2: Classical HL (which includes mixed cellularity, lymphocyte depleted and nodular sclerosis) shows the diagnostic Hodgkin and Reed-Sternberg (HRS) cells. Step 3: In contrast, the nodular lymphocyte-predominant subtype contains lymphocytic and histiocytic (L&H) cells, also called popcorn cells, rather than classic Reed-Sternberg cells. Step 4: Therefore the H and L cell variant corresponds to lymphocyte predominance Hodgkin lymphoma.
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