Question

Given below are two statements:
Statement I: Protein array is powerful proteomic technology using the fusion of microarray and ELISA on protein chip.
Statement II: Protein array is powerful genomic technology using enzyme structure and NMR for limited drug design
In the light of the above statements, choose the most appropriate answer from the options given below

• A. Both Statement I and Statement II are true
• B. Both Statement I and Statement II are false
• C. Statement I is correct but Statement II is false
• D. Statement I is incorrect but Statement II is true

Hint:

Protein Microarray (Protein Chip): High-throughput PROTEOMIC platform combining microarray spatial miniaturization with multiplexed ELISA-based capture.

Answer 1

The Correct Option is C

Step 1: Understanding the Concept:
Protein microarrays (protein chips) are high-throughput proteomic platforms immobilizing capture antibodies or purified proteins to parallelize miniaturized ELISA-like binding assays.

Step 2: Detailed Explanation:
1. Statement I: A Protein Microarray (Protein Chip) is a high-throughput proteomic technology that immobilizes thousands of capture proteins (antibodies, antigens, aptamers) at addressable microscopic spots on a solid glass/silicon chip surface, merging the spatial multiplexing of microarrays with the high sensitivity and specificity of enzyme-linked immunosorbent assays (ELISA). Hence, Statement I is correct.
2. Statement II: Protein microarrays are classified as proteomic (not genomic) technologies, and do not use nuclear magnetic resonance (NMR) spectroscopy for structural determination. Hence, Statement II is false.

Step 3: Final Answer:
Hence, Statement I is correct but Statement II is false, matching option (C).