Question:

Given below are two statements:
Statement (I): In rDNA technology, the transformation process generates a mixed population of transformed and non-transformed host cells.
Statement (II): In the screening process, both transformed and non-transformed host cells divide and redivide along with the replication of recombinant DNA.
In light of the above statements, choose the most appropriate answer from the options given below.

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Only some cells take up the rDNA, and screening picks out only the transformed ones.
Updated On: Nov 12, 2026
  • Both Statement (I) and Statement (II) are correct.
  • Both Statement (I) and Statement (II) are incorrect.
  • Statement (I) is correct but Statement (II) is incorrect.
  • Statement (I) is incorrect but Statement (II) is correct.
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The Correct Option is C

Solution and Explanation

Step 1: Understanding the Concept
Transformation is the uptake of recombinant DNA by host cells. It is not fully efficient.

Step 2: Statement (I)
Because only some host cells take up the rDNA, a mixed population of transformed and non-transformed cells is formed. Statement (I) is correct.

Step 3: Statement (II)
In screening, a selectable marker such as antibiotic resistance is used so that only transformed cells survive and multiply. Both types of cells do not keep dividing, so Statement (II) is incorrect.

Step 4: Conclusion
Statement (I) is correct but Statement (II) is incorrect.

Final Answer:
Statement (I) is correct and Statement (II) is incorrect. \[ \boxed{\text{(C) }\text{Statement (I) is correct but Statement (II) is incorrect.}} \]
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