Given below are two statements:
Assertion A: Polyclonal antibodies bind to the same antigen but recognize different epitopes.
Reason R: Polyclonal antibodies are produced by different B cell clones in the body.
Assertion A: Polyclonal antibodies bind to the same antigen but recognize different epitopes.
Reason R: Polyclonal antibodies are produced by different B cell clones in the body.
Show Hint
- Both A and R are correct and R is the correct explanation of A
- Both A and R are correct but R is not the correct explanation of A
- A is correct but R is not correct
- A is not correct but R is correct
The Correct Option is A
Solution and Explanation
Step 1: Concept
When an antigen enters the body, it often has multiple different structural features called epitopes.
Step 2: Meaning
Each individual B-cell is programmed to recognize only one specific epitope.
Step 3: Analysis
A complex antigen will trigger multiple different B-cells to proliferate and produce antibodies. Because these antibodies come from different B-cell clones, the resulting mixture is called "polyclonal." These antibodies all target the same overall antigen but bind to its various distinct epitopes.
Step 4: Conclusion
The assertion is true, and the reason correctly explains why the antibodies recognize multiple epitopes. Final Answer: (A)
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