Step 1: Concept
Antacids are classified into systemic (absorbable) and non-systemic (non-absorbable) types based on whether they enter the systemic circulation.
Step 2: Meaning
Systemic antacids are soluble and readily absorbed, which can potentially alter the blood pH and cause systemic alkalosis.
Step 3: Analysis
Sodium bicarbonate is highly water-soluble and is quickly absorbed into the bloodstream after neutralizing gastric acid. In contrast, aluminium hydroxide and calcium-based compounds are generally considered non-systemic as they remain largely in the gut.
Step 4: Conclusion
Because of its high solubility and systemic absorption, sodium bicarbonate is the classic example of a systemic antacid.
Final Answer: (A)