Question:
Enzymes of HMP shunt pathway are located in:
(A). Cytosol
(B). Plastids
(C). Mitochondria
(D). Peroxisomes
Choose the correct answer from the options given below:
Enzymes of HMP shunt pathway are located in:
(A). Cytosol
(B). Plastids
(C). Mitochondria
(D). Peroxisomes
Choose the correct answer from the options given below:
(A). Cytosol
(B). Plastids
(C). Mitochondria
(D). Peroxisomes
Choose the correct answer from the options given below:
Show Hint
Always distinguish between plant and animal biochemistry.
While most metabolic pathways are cytosolic in animals, plants possess duplicate pathways in plastids to support independent organellar metabolism.
While most metabolic pathways are cytosolic in animals, plants possess duplicate pathways in plastids to support independent organellar metabolism.
Updated On: Jul 31, 2026
- (A) and (D) only
- (A), (B) and (C) only
- (A), and (C) only
- (A) and (B) only
Show Solution
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The Correct Option is D
Solution and Explanation
Step 1: Understanding the Concept:
The Hexose Monophosphate (HMP) shunt, also known as the Pentose Phosphate Pathway (PPP), is an oxidative pathway parallel to glycolysis.
It generates $\text{NADPH}$ for reductive biosynthesis reactions and ribose 5-phosphate for nucleotide synthesis.
Step 2: Detailed Explanation:
In animal cells, the HMP shunt occurs exclusively in the cytosol.
However, plant cells contain two distinct and spatially separated sets of HMP shunt enzymes.
One pathway is localized in the Cytosol (A), where it interacts with glycolysis.
The other pathway is localized within the Plastids (B), such as chloroplasts in photosynthetic tissues or amyloplasts in non-photosynthetic tissues.
The plastidial pathway is essential for providing $\text{NADPH}$ required for nitrite reduction, fatty acid synthesis, and other anabolic processes in the dark.
Therefore, the enzymes are located in the Cytosol and Plastids.
Step 3: Final Answer:
The correct option is (A) and (B) only.
The Hexose Monophosphate (HMP) shunt, also known as the Pentose Phosphate Pathway (PPP), is an oxidative pathway parallel to glycolysis.
It generates $\text{NADPH}$ for reductive biosynthesis reactions and ribose 5-phosphate for nucleotide synthesis.
Step 2: Detailed Explanation:
In animal cells, the HMP shunt occurs exclusively in the cytosol.
However, plant cells contain two distinct and spatially separated sets of HMP shunt enzymes.
One pathway is localized in the Cytosol (A), where it interacts with glycolysis.
The other pathway is localized within the Plastids (B), such as chloroplasts in photosynthetic tissues or amyloplasts in non-photosynthetic tissues.
The plastidial pathway is essential for providing $\text{NADPH}$ required for nitrite reduction, fatty acid synthesis, and other anabolic processes in the dark.
Therefore, the enzymes are located in the Cytosol and Plastids.
Step 3: Final Answer:
The correct option is (A) and (B) only.
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