Question:
During synaptic fatigue, the transmission of nerve impulses across the synapse stops temporarily due to ______.
During synaptic fatigue, the transmission of nerve impulses across the synapse stops temporarily due to ______.
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Repeated stimulation uses up something that must be refilled in the synaptic vesicles.
Updated On: Nov 12, 2026
- strong stimulus more than threshold stimulus
- refractory period
- exhaustion of its neurotransmitter
- synaptic cleft of 20-30 nm
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The Correct Option is C
Solution and Explanation
Step 1: Understanding the Concept
At a chemical synapse, an impulse is passed on by neurotransmitter such as acetylcholine released from vesicles in the axon terminal.
Step 2: Repeated stimulation
When the presynaptic neuron is stimulated again and again at a high rate, vesicles are emptied faster than new transmitter can be made.
Step 3: Result
When the stock of neurotransmitter is used up, the postsynaptic membrane is not excited and transmission stops for a while until the transmitter is replaced. This is synaptic fatigue.
Final Answer:
Synaptic fatigue is caused by exhaustion of the neurotransmitter. \[ \boxed{\text{(C) }\text{exhaustion of its neurotransmitter}} \]
At a chemical synapse, an impulse is passed on by neurotransmitter such as acetylcholine released from vesicles in the axon terminal.
Step 2: Repeated stimulation
When the presynaptic neuron is stimulated again and again at a high rate, vesicles are emptied faster than new transmitter can be made.
Step 3: Result
When the stock of neurotransmitter is used up, the postsynaptic membrane is not excited and transmission stops for a while until the transmitter is replaced. This is synaptic fatigue.
Final Answer:
Synaptic fatigue is caused by exhaustion of the neurotransmitter. \[ \boxed{\text{(C) }\text{exhaustion of its neurotransmitter}} \]
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