Question:
Once the impulse has been transferred across a synapse, the neurotransmitter is destroyed by _____.
Once the impulse has been transferred across a synapse, the neurotransmitter is destroyed by _____.
Show Hint
Cholinesterase breaks down acetylcholine in the synaptic cleft.
Updated On: Nov 12, 2026
- adenylate cyclase
- cholinesterase
- cholinergic fibres
- catecholamines
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Verified By Collegedunia
The Correct Option is B
Solution and Explanation
Step 1: Understanding the Concept
After a neurotransmitter has acted on the postsynaptic membrane, it must be removed quickly.
Step 2: Removal of the neurotransmitter
The enzyme cholinesterase in the synaptic cleft hydrolyses acetylcholine into choline and acetic acid. Choline is taken back for reuse.
Step 3: Why the other options fail
Adenylate cyclase makes cyclic AMP. Cholinergic fibres are nerve fibres, and catecholamines are themselves transmitters or hormones.
Final Answer:
The neurotransmitter is destroyed by cholinesterase. \[ \boxed{\text{(B) }\text{cholinesterase}} \]
After a neurotransmitter has acted on the postsynaptic membrane, it must be removed quickly.
Step 2: Removal of the neurotransmitter
The enzyme cholinesterase in the synaptic cleft hydrolyses acetylcholine into choline and acetic acid. Choline is taken back for reuse.
Step 3: Why the other options fail
Adenylate cyclase makes cyclic AMP. Cholinergic fibres are nerve fibres, and catecholamines are themselves transmitters or hormones.
Final Answer:
The neurotransmitter is destroyed by cholinesterase. \[ \boxed{\text{(B) }\text{cholinesterase}} \]
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