Question:
Double-stranded circular form of DNA is present in all following cases except
Double-stranded circular form of DNA is present in all following cases except
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DNA Topology:
Circular dsDNA = Bacteria, Plasmids, Mitochondria, Chloroplasts.
Linear dsDNA = Eukaryotic Nuclear Chromosomes (with telomeres).
Circular dsDNA = Bacteria, Plasmids, Mitochondria, Chloroplasts.
Linear dsDNA = Eukaryotic Nuclear Chromosomes (with telomeres).
Updated On: Sep 4, 2026
- Eukaryotic chromosomal DNA
- Bacterial chromosomal DNA
- Mitochondrial DNA
- Chloroplast DNA
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The Correct Option is A
Solution and Explanation
Step 1: Understanding the Concept:
Genome topology distinguishes linear eukaryotic nuclear chromosomes (with telomeres) from covalently closed circular double-stranded DNA in bacteria and endosymbiotic organelles.
Step 2: Detailed Explanation:
Comparing DNA molecular topology:
1. Bacterial Chromosomes, Plasmids, Mitochondrial DNA (mtDNA), and Chloroplast DNA (cpDNA): All exist naturally as covalently closed, double-stranded circular DNA molecules reflecting their prokaryotic evolutionary origins (Endosymbiotic Theory).
2. Eukaryotic Nuclear Chromosomal DNA: Exists exclusively as linear double-stranded DNA organized with basic histone proteins into chromatin fibers and capped at both ends by specialized protective linear terminal structures called telomeres.
Step 3: Final Answer:
Thus, double-stranded circular DNA is absent in Eukaryotic chromosomal DNA, matching option (A).
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