Question:

Differentiate - Leading strand and Lagging strand.

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Remember: Leading = Continuous, Lagging = Okazaki fragments.
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Solution and Explanation

Concept: During DNA replication, the two strands are synthesized differently due to the antiparallel nature of DNA.
Step 1: Differences.
\[ \begin{array}{|c|c|c|} \hline Basis & Leading Strand & Lagging Strand
\hline Direction of synthesis & Same as replication fork & Opposite to replication fork
\hline Mode of synthesis & Continuous & Discontinuous
\hline Fragments & No fragments formed & Forms Okazaki fragments
\hline DNA polymerase action & Continuous addition & Requires repeated initiation
\hline Speed & Faster & Slower
\hline \end{array} \]
Step 2: Conclusion.
Thus, the leading strand is synthesized continuously, while the lagging strand is synthesized discontinuously.
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