Concept:
For the hyperbola
\[
\frac{x^2}{a^2}-\frac{y^2}{b^2}=1,
\]
the conjugate hyperbola is
\[
\frac{y^2}{b^2}-\frac{x^2}{a^2}=1.
\]
The ends of the transverse axis of the conjugate hyperbola are
\[
(0,b)
\quad\text{and}\quad
(0,-b).
\]
A circle having these two points as endpoints of a diameter can be obtained directly. After forming the circle, we find a tangent which is common to both the circle and the hyperbola. Equating the tangent conditions gives the required slope.
Step 1: Identify \(a\) and \(b\).
Given hyperbola:
\[
\frac{x^2}{25}-\frac{y^2}{16}=1.
\]
Comparing with
\[
\frac{x^2}{a^2}-\frac{y^2}{b^2}=1,
\]
we obtain
\[
a=5,
\qquad
b=4.
\]
Step 2: Write the conjugate hyperbola.
The conjugate hyperbola is
\[
\frac{y^2}{16}-\frac{x^2}{25}=1.
\]
Its transverse-axis endpoints are
\[
B(0,4),
\qquad
B'(0,-4).
\]
Step 3: Form the circle having \(BB'\) as diameter.
The midpoint of \(BB'\) is
\[
(0,0).
\]
The radius is
\[
4.
\]
Therefore the circle is
\[
x^2+y^2=16.
\]
Step 4: Take a common tangent with slope \(m\).
Let the common tangent be
\[
y=mx+c.
\]
For the circle
\[
x^2+y^2=16,
\]
the condition of tangency is
\[
c^2=16(1+m^2).
\]
\[
c=\pm4\sqrt{1+m^2}.
\]
Step 5: Use tangency condition for the hyperbola.
For
\[
\frac{x^2}{25}-\frac{y^2}{16}=1,
\]
a tangent of slope \(m\) is
\[
y=mx\pm\sqrt{25m^2-16}.
\]
Thus
\[
c^2=25m^2-16.
\]
Step 6: Equate the two values of \(c^2\).
Since the same line is tangent to both curves,
\[
16(1+m^2)=25m^2-16.
\]
Expanding,
\[
16+16m^2=25m^2-16.
\]
\[
32=9m^2.
\]
\[
m^2=\frac{32}{9}.
\]
\[
m=\pm\frac{4\sqrt2}{3}.
\]
Step 7: Final Conclusion.
Therefore the slope of the common tangent is
\[
\boxed{\pm\frac{4\sqrt2}{3}}.
\]
Hence the correct answer is
\[
\boxed{\text{Option (B)}}.
\]