Question:

Choose the correct statements among the following: A) Transcriptase catalyzes the polymerization in 5' $\rightarrow$ 3' direction only and the 3' $\rightarrow$ 5' strand is referred to as template. B) The chemical method of Khorana was instrumental in the synthesis of homopolymers of RNA. C) tRNA amino acid acceptor end has bases complementary to the code. D) 23s r-RNA in bacteria is a ribozyme.

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Ribozymes are RNAs that catalyze reactions; 23S rRNA is the "heart" of the ribosome!
Updated On: Jun 10, 2026
  • A, B, C
  • B, C, D
  • A, C, D
  • A, B, D
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The Correct Option is D

Solution and Explanation

Step 1: Concept
Molecular genetics, transcription, and translation processes.

Step 2: Analysis
* Statement A is correct: Transcription occurs in the 5' $\rightarrow$ 3' direction using the 3' $\rightarrow$ 5' strand as a template. * Statement B is correct: Khorana's chemical method helped synthesize RNA homopolymers, essential for deciphering the genetic code. * Statement C is incorrect: The amino acid acceptor end (CCA-OH) of tRNA attaches to the amino acid, while the anticodon loop contains bases complementary to the mRNA codon. * Statement D is correct: 23S rRNA acts as a ribozyme (peptidyl transferase) in bacterial ribosomes.

Step 3: Conclusion
Statements A, B, and D are correct.

Final Answer: (D)
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