Question:

Assertion (A): Scleroderma is a systemic autoimmune disease. Reason (R): In Scleroderma, immune response is directed toward nuclei, heart, lungs, kidney and gastrointestinal tract.

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Systemic = The whole system. If it attacks the heart, lungs, and kidneys, it's systemic!
Updated On: May 28, 2026
  • Both (A) and (R) are correct and (R) is the correct explanation of (A).
  • Both (A) and (R) are correct but (R) is NOT the correct explanation of (A).
  • (A) is correct but (R) is not correct.
  • (A) is not correct but (R) is correct.
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The Correct Option is A

Solution and Explanation

Step 1: Concept
Autoimmune diseases occur when the immune system attacks the body's own tissues.

Step 2: Meaning

“Systemic” means it affects multiple organs throughout the body.

Step 3: Analysis

Assertion (A) correctly identifies Scleroderma as systemic. Reason (R) lists the various internal organs targeted. Because it attacks all these different systems, it is classified as systemic.

Step 4: Conclusion

(R) is the direct evidence and explanation for why the disease is called “systemic” (A).

Final Answer: (A)
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