Major Histocompatibility Complex I (MHC-I) molecules present intracellular antigens to CD8+ cytotoxic T-cells, playing a crucial role in immune responses against viral infections and cancer.
| List I (Genetic Disorders) | List II (Genetic Alteration) | ||
| A | Down syndrome | I | Gain of X-chromosome |
| B | Klinefelter's syndrome | II | Loss of X-chromosome |
| C | Turner's syndrome | III | Trisomy of chromosome 21 |
| D | Cri du chat syndrome | IV | Deletion of small terminal portion of chromosome 5 |
Choose the correct answer from the options given below: