Question:
Arrange the following in a sequential order:
1. Exposure of collagen
2. Formation of platelet plug
3. Production of web of fibrin proteins
4. Vaso constriction
Arrange the following in a sequential order:
1. Exposure of collagen
2. Formation of platelet plug
3. Production of web of fibrin proteins
4. Vaso constriction
1. Exposure of collagen
2. Formation of platelet plug
3. Production of web of fibrin proteins
4. Vaso constriction
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Hemostasis occurs in three stages: vascular spasm, platelet plug formation, and coagulation.
Updated On: Jun 19, 2026
- 1, 4, 2, 3
- 1, 2, 3, 4
- 4, 3, 2, 1
- 2, 3, 4, 2
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The Correct Option is A
Solution and Explanation
Step 1: Understand hemostasis process.
Hemostasis is the physiological process that prevents blood loss from damaged blood vessels through a sequence of well-coordinated events.
Step 2: Identify initial response.
The first response to blood vessel injury is vasoconstriction (4), which reduces blood flow to the damaged area.
Step 3: Exposure of collagen.
Damage to the endothelium exposes collagen fibers (1), which triggers platelet adhesion at the injury site.
Step 4: Platelet plug formation.
Platelets adhere to exposed collagen and aggregate to form a temporary platelet plug (2).
Step 5: Formation of fibrin network.
The coagulation cascade leads to the formation of fibrin threads, producing a stable clot or web of fibrin proteins (3).
Step 6: Final sequence confirmation.
Thus, the correct physiological sequence is vasoconstriction → collagen exposure → platelet plug formation → fibrin clot formation, i.e., 4 → 1 → 2 → 3 (Option 1).
Hemostasis is the physiological process that prevents blood loss from damaged blood vessels through a sequence of well-coordinated events.
Step 2: Identify initial response.
The first response to blood vessel injury is vasoconstriction (4), which reduces blood flow to the damaged area.
Step 3: Exposure of collagen.
Damage to the endothelium exposes collagen fibers (1), which triggers platelet adhesion at the injury site.
Step 4: Platelet plug formation.
Platelets adhere to exposed collagen and aggregate to form a temporary platelet plug (2).
Step 5: Formation of fibrin network.
The coagulation cascade leads to the formation of fibrin threads, producing a stable clot or web of fibrin proteins (3).
Step 6: Final sequence confirmation.
Thus, the correct physiological sequence is vasoconstriction → collagen exposure → platelet plug formation → fibrin clot formation, i.e., 4 → 1 → 2 → 3 (Option 1).
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