Question

An amino acid structural unit present in a captopril is

• A. Serine
• B. Proline
• C. Alanine
• D. Methionine

Hint:

Proline is the cyclic amino acid in Captopril.

Answer 1

The Correct Option is B

Step 1: Concept
Captopril is an ACE inhibitor used for hypertension.

Step 2: Meaning
Many drugs are designed by incorporating structural analogs or actual units of amino acids.

Step 3: Analysis
Chemically, captopril is (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid. The pyrrolidine-2-carboxylic acid moiety is the structure of the amino acid proline.

Step 4: Conclusion
Therefore, Proline is the amino acid unit found within the captopril molecule.

Final Answer: (B)