Question

A patient presents with a combination of the following signs: lower lip swelling, facial nerve palsy, and a tongue with fissuresWhich syndrome is most likely?

• A. Pierre Robin sequence
• B. Parry-Romberg syndrome
• C. Melkersson-Rosenthal syndrome
• D. Guillain-Barré syndrome

Hint:

Melkersson-Rosenthal = Lip swelling + Facial palsy + Fissured tongue (Classical triad).

Answer 1

The Correct Option is C

Step 1: Identifying the Classical Triad.
The patient presents with lower lip swelling, facial nerve palsy, and fissured tongueThis combination represents a classical triad seen in a specific neurological disorder
Step 2: Understanding Melkersson-Rosenthal Syndrome.
Melkersson-Rosenthal syndrome is characterized by:
• Recurrent orofacial swelling (especially lips)
• Facial nerve palsy
• Fissured tongue (lingua plicata)
The presence of all three strongly suggests this diagnosis
Step 3: Eliminating Other Options.
(A) Pierre Robin sequence involves micrognathia, glossoptosis, and cleft palate
(B) Parry-Romberg syndrome causes progressive hemifacial atrophy
(D) Guillain-Barré syndrome is an acute demyelinating neuropathy affecting peripheral nerves
Step 4: Conclusion.
The triad of lip swelling, facial palsy, and fissured tongue confirms Melkersson-Rosenthal syndrome