Question

A female patient presents with white, curd-like lesions on the buccal mucosa. A biopsy confirms the diagnosis of oral thrush. Which is the most appropriate topical antifungal treatment?

• A. Clotrimazole
• B. Neomycin
• C. Fluconazole
• D. Griseofulvin

Hint:

For mild oral candidiasis, use topical agents like clotrimazole or nystatin before considering systemic antifungals.

Answer 1

The Correct Option is A

Step 1: Identifying the Condition.
White, curd-like lesions on the buccal mucosa that can be wiped off are characteristic of pseudomembranous candidiasis (oral thrush)It is caused by \textit{Candida albicans} infection
Step 2: Treatment Principle.
Management of oral thrush typically involves topical antifungal agents in mild to moderate casesTopical therapy is preferred initially because it provides high local concentration with minimal systemic side effects
Step 3: Evaluation of Options.
(A) Clotrimazole: CorrectIt is an imidazole antifungal used topically in the form of lozenges or troches and is effective against oral candidiasis
(B) Neomycin: An antibiotic used for bacterial infections, not fungal infections
(C) Fluconazole: A systemic antifungal agent usually reserved for severe or refractory cases
(D) Griseofulvin: Used mainly for dermatophyte infections, not for oral candidiasis
Step 4: Conclusion.
Therefore, the most appropriate topical antifungal treatment for oral thrush is clotrimazole