Question:
A patient on long-term hydrochlorothiazide develops neuropathy, heart failure, and symmetrical paresthesia. Which nutrient deficiency is most likely responsible?
A patient on long-term hydrochlorothiazide develops neuropathy, heart failure, and symmetrical paresthesia. Which nutrient deficiency is most likely responsible?
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Thiamine deficiency causes dry beriberi with neuropathy and wet beriberi with heart failure.
Updated On: May 14, 2026
- Selenium
- Thiamine
- Vitamin B12
- Zinc
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The Correct Option is B
Solution and Explanation
Concept:
Thiamine deficiency can cause neuropathy and cardiac failure. It is associated with beriberi.
Step 1: Identify symptoms.
The patient has: \[ \text{Neuropathy + paresthesia + heart failure} \] This suggests thiamine deficiency.
Step 2: Recall thiamine deficiency syndromes.
Thiamine deficiency causes: \[ \text{Dry beriberi} = \text{neuropathy} \] \[ \text{Wet beriberi} = \text{heart failure} \]
Step 3: Choose the nutrient.
Therefore, the most likely deficiency is: \[ \text{Thiamine} \]
Step 1: Identify symptoms.
The patient has: \[ \text{Neuropathy + paresthesia + heart failure} \] This suggests thiamine deficiency.
Step 2: Recall thiamine deficiency syndromes.
Thiamine deficiency causes: \[ \text{Dry beriberi} = \text{neuropathy} \] \[ \text{Wet beriberi} = \text{heart failure} \]
Step 3: Choose the nutrient.
Therefore, the most likely deficiency is: \[ \text{Thiamine} \]
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