A DNA sequence has two ends, 5' and 3'. Which of the following statements is correct regarding the nature of the ends?
Show Hint
- The 5' end has a hydroxyl group.
- The 5' end has a phosphate group.
- The 3' end has a phosphate group.
- Any group can be present at any end.
The Correct Option is B
Solution and Explanation
Step 1: Concept
DNA strands have a specific polarity based on the structure of the deoxyribose sugar.
Step 2: Meaning
The 5' and 3' designations refer to the carbon atoms of the sugar molecule.
Step 3: Analysis
The 5' carbon is typically attached to a phosphate group, while the 3' carbon has a free hydroxyl ($-OH$) group.
Step 4: Conclusion
Therefore, the 5' end is characterized by a phosphate group. Final Answer: (B)
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