List of top Questions asked in NEET SS- 2024

A 52-year-old patient is found to have a liver lesion during an ultrasound examination performed for abdominal discomfort. The lesion’s nature is unclear on ultrasound. To further characterize this lesion and assist in diagnosis and management planning, what is the next best imaging investigation?
A patient undergoing therapeutic phlebotomy every two weeks shows a decrease in hemoglobin from 18 mg/dL to 14 mg/dL. As the hemoglobin approaches normal levels, the frequency of phlebotomy needs adjustment to maintain target hemoglobin and prevent anemia. What should be the next step regarding the interval of phlebotomy?
A 45-year-old man with a history of heavy weekend alcohol consumption is brought to the emergency department with confusion, hallucinations, and ataxia. His friends report that he had been vomiting for two days and had poor oral intake before the episode. On examination, he is disoriented with horizontal nystagmus and unsteady gait.
Options:
A patient is diagnosed with hepatocellular carcinoma (HCC) measuring 5 cm. What is the treatment of choice?
A 35-year-old healthy female donor is found to be HBsAg positive during routine blood donation screening. She is asymptomatic with no known liver disease. As part of evaluating her infectious status and risk of disease progression, what is the next best step in her evaluation?
A 48-year-old male with acute hepatic failure is being evaluated for liver transplantation. His urine test shows ethylene glycol positivity. Which of the following constitutes an absolute contraindication to liver transplantation?
A 22-year-old male presents with progressive tremors, slurred speech, and personality changes over the past few months. On examination, he has mild hepatomegaly, dysarthria, and a brownish ring around the cornea visible on slit-lamp examination (Kayser–Fleischer ring). Laboratory evaluation shows mildly elevated liver enzymes. Which of the following is the definitive diagnostic test for Wilson’s disease?
A 35-year-old man with a 5-year history of ulcerative colitis presents with mild jaundice and fatigue. Liver function tests show mildly elevated ALT and markedly elevated ALP. Ultrasound of the abdomen reveals a normal biliary tree with no stones or ductal dilatation. Which antibody is most likely elevated in this patient?
A 48-year-old woman presents with progressive fatigue and pruritus. Laboratory tests reveal markedly elevated alkaline phosphatase and mild elevation of transaminases. Ultrasound shows normal bile ducts. Which of the following antibodies is most likely to be positive in this patient?
A 28-year-old woman presents with fatigue, jaundice, and elevated liver enzymes. Autoimmune markers are positive for ANA and anti-smooth muscle antibody, and a liver biopsy confirms autoimmune hepatitis. She is started on corticosteroids. Which of the following drugs should be added to steroids to maintain remission and minimize steroid toxicity?
A 52-year-old man with long-standing alcohol use presents with jaundice and mild ascites. Laboratory tests show total bilirubin of 4.8 mg/dL, AST 48 U/L, ALT 45 U/L, and INR 1.8. Viral hepatitis serology is negative, and ultrasound shows a coarse echotexture liver with features of portal hypertension. What is the most appropriate method to determine the cause of cirrhosis in this patient?
A 58-year-old man presents with left lower quadrant pain, low-grade fever, and leukocytosis. CT abdomen shows diverticulitis with a small pericolic abscess. What is the first step in management?
A 48-year-old man undergoing chemotherapy for acute myeloid leukemia presents with high-grade fever, chills, and hypotension. Laboratory tests show an absolute neutrophil count (ANC) of 300 cells/$mm^3$. Blood cultures are pending. Which of the following organisms is most commonly responsible for sepsis in patients with febrile neutropenia?
A 28-year-old woman in her third trimester presents with jaundice, malaise, and elevated liver enzymes. Serology confirms Hepatitis E infection. Which of the following statements regarding Hepatitis E infection in pregnancy is true?
A 45-year-old patient with acute myeloid leukemia undergoing chemotherapy develops high-grade fever with chills and a total leukocyte count of 400 cells/$mm^3$. Blood pressure is stable, but the patient has mucositis and no localizing source of infection. Which of the following is the most appropriate empirical antibiotic regimen to start?
A 32-year-old woman with relapsing-remitting multiple sclerosis presents with a positive Lhermitte sign indicating cervical cord involvement. She has low JC virus antibody titers and wishes to conceive in the future. Which of the following disease-modifying therapies is most appropriate for her?
A 35-year-old man from Bihar presents with prolonged fever, weight loss, and hepatosplenomegaly. Laboratory findings show pancytopenia. Which of the following is considered the gold standard investigation for confirming the diagnosis of leishmaniasis?
A 28-year-old pregnant woman in her first trimester undergoes routine antenatal evaluation. Urine culture reveals $>$100,000 CFU/mL of E. coli, but she remains asymptomatic. What is the most appropriate next step in management?
what is the most common cause of reactive arthritis in a patient with diarrhea and dysuria?
A 42-year-old HIV-positive patient on antiretroviral therapy with stavudine presents with progressive motor weakness, tingling in the limbs, hepatomegaly, and metabolic acidosis. Laboratory evaluation shows elevated serum lactate levels, and neurological examination reveals large fiber sensory loss. What is the most likely diagnosis?
A 7-year-old unvaccinated child presents with a history of sore throat and fever 3 weeks ago. The child now develops nasal regurgitation of fluids, facial deviation, and tongue weakness with numbness. On examination, there is palatal paralysis and a nasal twang to the voice. What is the most likely diagnosis?
A 60-year-old man presents with high-grade fever, headache, neck stiffness, and altered sensorium. Cerebrospinal fluid (CSF) examination is pending, but clinical findings are highly suggestive of bacterial meningitis. Which empirical antibiotic regimen should be started immediately?
A 45-year-old man on antitubercular therapy is found to have a rifampicin-resistant strain of Mycobacterium tuberculosis on GeneXpert testing. Which of the following best explains the mechanism of resistance?
A 45-year-old man presents with chronic diarrhea, significant weight loss, and arthralgia. Endoscopic biopsy of the small intestine reveals numerous foamy macrophages in the lamina propria that stain positive with Periodic Acid–Schiff (PAS). What is the most likely diagnosis?
What is the drug of choice in the treatment of liver abscess?