Question:
Which type of mutation causes sickle cell anaemia?
Which type of mutation causes sickle cell anaemia?
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Sickle cell anaemia comes from a single base pair change.
Updated On: Nov 13, 2026
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The Correct Option is D
Solution and Explanation
Step 1: Understanding the Concept
Sickle cell anaemia is due to substitution of one base (GAG to GUG) in the beta globin gene.
Step 2: Result
This replaces glutamic acid with valine at the sixth position, so it is a point mutation.
Step 3: Conclusion
Therefore, sickle cell anaemia is caused by a point mutation.
Final Answer:
Sickle cell anaemia is caused by a point mutation. \[ \boxed{\text{(D) }\text{Point}} \]
Sickle cell anaemia is due to substitution of one base (GAG to GUG) in the beta globin gene.
Step 2: Result
This replaces glutamic acid with valine at the sixth position, so it is a point mutation.
Step 3: Conclusion
Therefore, sickle cell anaemia is caused by a point mutation.
Final Answer:
Sickle cell anaemia is caused by a point mutation. \[ \boxed{\text{(D) }\text{Point}} \]
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