Question

Which type of Inhibition is most noticeable at low substrate concentration, and can be overcome by higher substrate concentration?

• A. Noncompetitive inhibition
• B. Competitive inhibition
• C. Suicidal inhibition
• D. Uncompetitive inhibition

Hint:

Competitive inhibition: inhibitor competes with substrate.
Overcome by high substrate concentration.
Vmax unchanged, Km increased.

Answer 1

The Correct Option is B

Step 1: Understanding the Concept:
Enzyme inhibition can be of different types.
Each type has specific characteristics.

Step 2: Key Formula or Approach:
No specific formula.
Need to understand the types of enzyme inhibition.

Step 3: Detailed Explanation:
Competitive inhibition is most noticeable at low substrate concentration.
It can be overcome by increasing substrate concentration.
This is because the inhibitor and substrate compete for the active site.
Noncompetitive inhibition cannot be overcome by substrate.
Suicidal inhibition is irreversible.
Uncompetitive inhibition binds to the enzyme-substrate complex.
Thus, competitive inhibition is the correct answer.

Step 4: Final Answer:
Competitive inhibition is overcome by higher substrate concentration.
Hence, the correct option is (B).