Step 1: Understanding the Concept
Genetic drift is a random change in allele frequency, also called the Sewall Wright effect.
Step 2: Check each statement
It occurs by chance, so it is directionless. When a few individuals found a new small population in a new area, drift acts strongly.
Step 3: Find the incorrect one
Random changes alter allele frequencies noticeably only in small populations. In large populations they average out, so drift is not more significant there.
Final Answer:
The statement that drift is more significant in large populations is incorrect.
\[ \boxed{\text{(B) }\text{The effect of genetic drift is more significant in large populations.}} \]