Question:
Which one of the following is an exogenous pigmentation?
Which one of the following is an exogenous pigmentation?
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An easy way to classify pigments is to ask: "Did this substance originate inside the body?" Melanin, lipofuscin, and hemosiderin are made by cells, while tattoo ink enters from the outside world.
Updated On: Aug 3, 2026
- Lipofuschinosis
- Tattooing
- Melanosis
- Hemosiderosis
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Verified By Collegedunia
The Correct Option is B
Solution and Explanation
Step 1: Understanding the Concept:
Pathological pigmentation involves the abnormal accumulation of colored substances within tissues.
These pigments are classified as endogenous (produced inside the body) or exogenous (introduced from the external environment).
Step 2: Detailed Explanation:
Let us analyze each type of pigmentation listed:
- Tattooing: This is a classic example of exogenous pigmentation. Insoluble, non-toxic mineral or vegetable pigments (such as carbon, ink, or coal dust) are introduced into the dermis from the outside environment. Once introduced, these pigments are engulfed by dermal macrophages and remain permanently in the extracellular matrix or within phagocytic cells. Other exogenous pigments include carbon (anthracosis), lead (plumbism), and silica (silicosis).
- Lipofuschinosis: This is an endogenous pigmentation characterized by the accumulation of lipofuscin. This "wear-and-tear" or aging pigment is composed of lipid-protein complexes resulting from the oxidation of unsaturated fatty acids in lysosomes.
- Melanosis: This is an endogenous accumulation of melanin, a natural pigment synthesized by melanocytes.
- Hemosiderosis: This is an endogenous pigmentation caused by the accumulation of hemosiderin, an iron-rich pigment derived from the breakdown of hemoglobin during red blood cell destruction.
Therefore, tattooing is the only exogenous pigmentation among the options.
Step 3: Final Answer:
The exogenous pigmentation is Tattooing, corresponding to option (B).
Pathological pigmentation involves the abnormal accumulation of colored substances within tissues.
These pigments are classified as endogenous (produced inside the body) or exogenous (introduced from the external environment).
Step 2: Detailed Explanation:
Let us analyze each type of pigmentation listed:
- Tattooing: This is a classic example of exogenous pigmentation. Insoluble, non-toxic mineral or vegetable pigments (such as carbon, ink, or coal dust) are introduced into the dermis from the outside environment. Once introduced, these pigments are engulfed by dermal macrophages and remain permanently in the extracellular matrix or within phagocytic cells. Other exogenous pigments include carbon (anthracosis), lead (plumbism), and silica (silicosis).
- Lipofuschinosis: This is an endogenous pigmentation characterized by the accumulation of lipofuscin. This "wear-and-tear" or aging pigment is composed of lipid-protein complexes resulting from the oxidation of unsaturated fatty acids in lysosomes.
- Melanosis: This is an endogenous accumulation of melanin, a natural pigment synthesized by melanocytes.
- Hemosiderosis: This is an endogenous pigmentation caused by the accumulation of hemosiderin, an iron-rich pigment derived from the breakdown of hemoglobin during red blood cell destruction.
Therefore, tattooing is the only exogenous pigmentation among the options.
Step 3: Final Answer:
The exogenous pigmentation is Tattooing, corresponding to option (B).
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