Concept:
• Plasmodium is a microscopic, single-celled protozoan parasite that causes malaria.
• It has a complex, two-host (digenetic) life cycle:
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• Asexual cycle (in Humans): Sporozoites migrate to liver cells and reproduce asexually (schizogony). They then infect red blood cells (RBCs), reproducing asexually to release merozoites.
• Sexual stages (Gametocytes): Form and develop inside human RBCs.
• Sexual cycle (in Mosquitoes): Gametocytes are ingested by the female Anopheles mosquito, mature into gametes, and undergo
fertilization inside the mosquito's gut.
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Step 1: Evaluate the statements on sexual vs. asexual phases
Option (A) is correct: Fertilization of male and female microgametes occurs in the intestinal lumen of the mosquito.
Option (B) and (C) are incorrect: Plasmodium reproduces asexually in human liver cells and RBCs.
Option (D) is incorrect: Gametocytes are produced and develop in human blood (RBCs), not inside the mosquito.