Question

Which of the following statements are true with the Adverse Drug Reactions?
A. Any response to a drug which is noxious and unintended. 
B. Which occurs at doses normally used in man for prophylaxis, diagnosis or therapy of a disease. 
C. Adverse drug event is same as that of Adverse Drug Reaction. 
D. Which occurs at normal dose or overdose when used for prophylaxis, diagnosis or therapy of a disease. 
Choose the correct answer from the options given below:

• A. A and B are true while C and D are false.
• B. A and C are true while B and D are false.
• C. B, C and D are false, Only A is true.
• D. A, B and C are false, Only D is true.

Answer 1

The Correct Option is A

The question asks about the truthfulness of statements regarding Adverse Drug Reactions (ADRs). Let's analyze each statement to determine the correctness:

1. Statement A: "Any response to a drug which is noxious and unintended."
   This statement is true. Adverse Drug Reactions are defined as any harmful, unintended response to a medication that occurs at doses normally used for therapeutic purposes. This aligns with the official definition provided by organizations like the World Health Organization (WHO).
2. Statement B: "Which occurs at doses normally used in man for prophylaxis, diagnosis or therapy of a disease."
   This statement is also true. ADRs are unwanted effects that occur when a drug is prescribed and consumed at typical doses for prevention, diagnosis, or treatment.
3. Statement C: "Adverse drug event is the same as that of Adverse Drug Reaction."
   This statement is false. An adverse drug event (ADE) is a broader term encompassing any harm experienced by a patient from a medication, including overdoses and medication errors, while ADR is specifically about noxious and unintended responses at normal dosage.
4. Statement D: "Which occurs at normal dose or overdose when used for prophylaxis, diagnosis or therapy of a disease."
   This statement is false. While ADRs occur at normal therapeutic use, the mention of overdose falls under ADEs, not ADRs specifically.

Based on the analysis above, the correct answer is: A and B are true while C and D are false.