Question:
Which of the following is the precursor of coenzyme that participates in one carbon group transfer in purine synthesis?
Which of the following is the precursor of coenzyme that participates in one carbon group transfer in purine synthesis?
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Folic acid \(\rightarrow\) THF.
THF involved in one-carbon transfer.
Required for purine synthesis.
THF involved in one-carbon transfer.
Required for purine synthesis.
Updated On: Aug 18, 2026
- Biotin
- Cobalamine
- Thiamine
- Folic acid
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Verified By Collegedunia
The Correct Option is D
Solution and Explanation
Step 1: Understanding the Concept:
One-carbon group transfer is important in purine synthesis.
Specific coenzymes are involved.
Step 2: Key Formula or Approach:
No specific formula.
Need to know the coenzymes involved in one-carbon transfer.
Step 3: Detailed Explanation:
Folic acid (folate) is the precursor of tetrahydrofolate (THF).
THF is the coenzyme involved in one-carbon group transfer.
It is required for purine and pyrimidine synthesis.
Biotin is for carboxylation.
Cobalamine (B12) is for methyl transfer.
Thiamine (B1) is TPP.
Thus, folic acid is the precursor.
Step 4: Final Answer:
Folic acid is the precursor of the coenzyme for one-carbon transfer.
Hence, the correct option is (D).
One-carbon group transfer is important in purine synthesis.
Specific coenzymes are involved.
Step 2: Key Formula or Approach:
No specific formula.
Need to know the coenzymes involved in one-carbon transfer.
Step 3: Detailed Explanation:
Folic acid (folate) is the precursor of tetrahydrofolate (THF).
THF is the coenzyme involved in one-carbon group transfer.
It is required for purine and pyrimidine synthesis.
Biotin is for carboxylation.
Cobalamine (B12) is for methyl transfer.
Thiamine (B1) is TPP.
Thus, folic acid is the precursor.
Step 4: Final Answer:
Folic acid is the precursor of the coenzyme for one-carbon transfer.
Hence, the correct option is (D).
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