Question:

Which of the following is involved in epistasis?

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Remember: "Epi-" means upon or over, indicating a hierarchical masking effect of one gene over another gene at a different locus (intergenic).
This is distinct from dominance, which represents the interaction of alleles of the same gene (intragenic).
  • Intragenic interaction
  • Interallelic interaction
  • Intergenic interaction
  • Gene conversion
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The Correct Option is C

Solution and Explanation

Step 1: Understanding the Concept:
Epistasis is a genetic phenomenon where the effect of one gene locus is masked or modified by the expression of one or more other gene loci.

Step 3: Detailed Explanation:

Genetic interactions can be categorized into two main types:
1. Intragenic (or allelic) interactions: Interactions occurring between alleles of the same gene locus (e.g., dominance, co-dominance, incomplete dominance).
2. Intergenic (or non-allelic) interactions: Interactions occurring between genes located at different loci on the chromosomes.
Since epistasis involves a gene at one locus masking or modifying the phenotypic expression of another gene at a different locus, it is classified as an intergenic interaction.

Step 4: Final Answer

The correct option is (C).
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