Question:
Which of the following is a proton pump inhibitor?
Which of the following is a proton pump inhibitor?
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Look for the drug whose name ends in -prazole.
Updated On: Jun 24, 2026
- Ranitidine
- Misoprostol
- Omeprazole
- Lafutidine
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The Correct Option is C
Solution and Explanation
Step 1: Recall what a proton pump inhibitor (PPI) does. PPIs irreversibly block the \(H^{+}/K^{+}\) ATPase (the proton pump) on the luminal side of gastric parietal cells, which is the final common step of acid secretion. This gives strong, lasting suppression of stomach acid.
Step 2: Identify omeprazole. Omeprazole is the prototype PPI, and the suffix '-prazole' marks the whole class (pantoprazole, lansoprazole, rabeprazole, esomeprazole). So option C is the proton pump inhibitor.
Step 3: Rule out the rest. Ranitidine (A) is an \(H_2\) receptor blocker, not a PPI. Misoprostol (B) is a prostaglandin \(E_1\) analogue used to protect gastric mucosa. Lafutidine (D) is also an \(H_2\) receptor antagonist.
Answer: Option C (Omeprazole).
Step 2: Identify omeprazole. Omeprazole is the prototype PPI, and the suffix '-prazole' marks the whole class (pantoprazole, lansoprazole, rabeprazole, esomeprazole). So option C is the proton pump inhibitor.
Step 3: Rule out the rest. Ranitidine (A) is an \(H_2\) receptor blocker, not a PPI. Misoprostol (B) is a prostaglandin \(E_1\) analogue used to protect gastric mucosa. Lafutidine (D) is also an \(H_2\) receptor antagonist.
Answer: Option C (Omeprazole).
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