Question

Which of the following intermediates of Krebs cycle undergoes both oxidation and decarboxylation reactions?

• A. Oxalo acetate
• B. Oxalo succinate
• C. α - ketoglutarate
• D. Succinyl Co-A

Hint:

The Krebs cycle involves both oxidation and decarboxylation reactions to generate energy-rich molecules like ATP.

Answer 1

The Correct Option is C

Step 1: Understanding the Krebs cycle intermediates.
In the Krebs cycle, α-ketoglutarate undergoes both oxidation and decarboxylation. It is converted to succinyl CoA through these processes, releasing energy.
Step 2: Analyzing the options.
(A) Oxalo acetate: Incorrect, oxaloacetate is involved in the cycle but does not undergo both oxidation and decarboxylation.
(B) Oxalo succinate: Incorrect, this is an intermediate but not the one that undergoes both oxidation and decarboxylation.
(C) α - ketoglutarate: Correct, α-ketoglutarate undergoes both oxidation and decarboxylation to form succinyl CoA.
(D) Succinyl Co-A: Incorrect, succinyl CoA is formed after α-ketoglutarate, and it does not undergo oxidation or decarboxylation.
Step 3: Conclusion.
The correct answer is (C) α - ketoglutarate, as it undergoes both oxidation and decarboxylation in the Krebs cycle.