Question:
Which of the following group of compounds is produced by Streptomyces hygroscopicus ?
Which of the following group of compounds is produced by Streptomyces hygroscopicus ?
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Milbemycin oxime is a derivative widely used in veterinary medicine as an antiparasitic agent to control heartworms and hookworms in pets.
It is closely related to the avermectin family.
It is closely related to the avermectin family.
Updated On: Jul 23, 2026
- Tetranactin
- Avermectins
- Strobilurins
- Milbemycin
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Verified By Collegedunia
The Correct Option is D
Solution and Explanation
Step 1: Understanding the Concept:
Soil actinomycetes, particularly species of the genus *Streptomyces*, are valuable sources of biologically active secondary metabolites.
These metabolites are widely used in agriculture as natural antibiotics, insecticides, acaricides, and fungicides.
Step 3: Detailed Explanation:
Let us analyze the biological origins of the listed compounds:
1. Tetranactin:
This macrotetrolide antibiotic is produced by *Streptomyces aureus*.
Thus, Option (A) is incorrect.
2. Avermectins:
This group of insecticidal and anthelmintic compounds is produced by the soil bacterium *Streptomyces avermitilis*.
Thus, Option (B) is incorrect.
3. Strobilurins:
This class of natural fungicides was originally isolated from the wood-rotting mushroom fungus *Strobilurus tenacellus*, not a bacterium.
Thus, Option (C) is incorrect.
4. Milbemycins:
Milbemycins are a group of macrolide compounds with potent acaricidal and insecticidal activity.
They are produced by fermenting the soil actinomycete *Streptomyces hygroscopicus* (specifically *Streptomyces hygroscopicus* subsp. *aureolacrimosus*).
They function by opening glutamate-gated chloride channels in the nervous systems of insects and mites.
Step 4: Final Answer:
The group of compounds produced by *Streptomyces hygroscopicus* is Milbemycin.
Therefore, the correct option is (D).
Soil actinomycetes, particularly species of the genus *Streptomyces*, are valuable sources of biologically active secondary metabolites.
These metabolites are widely used in agriculture as natural antibiotics, insecticides, acaricides, and fungicides.
Step 3: Detailed Explanation:
Let us analyze the biological origins of the listed compounds:
1. Tetranactin:
This macrotetrolide antibiotic is produced by *Streptomyces aureus*.
Thus, Option (A) is incorrect.
2. Avermectins:
This group of insecticidal and anthelmintic compounds is produced by the soil bacterium *Streptomyces avermitilis*.
Thus, Option (B) is incorrect.
3. Strobilurins:
This class of natural fungicides was originally isolated from the wood-rotting mushroom fungus *Strobilurus tenacellus*, not a bacterium.
Thus, Option (C) is incorrect.
4. Milbemycins:
Milbemycins are a group of macrolide compounds with potent acaricidal and insecticidal activity.
They are produced by fermenting the soil actinomycete *Streptomyces hygroscopicus* (specifically *Streptomyces hygroscopicus* subsp. *aureolacrimosus*).
They function by opening glutamate-gated chloride channels in the nervous systems of insects and mites.
Step 4: Final Answer:
The group of compounds produced by *Streptomyces hygroscopicus* is Milbemycin.
Therefore, the correct option is (D).
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