Question:
Which of the following database do not store nucleic acid data?
Which of the following database do not store nucleic acid data?
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The INSDC databases (GenBank, EMBL, and DDBJ) host global nucleotide data, whereas SWISS-PROT is reserved solely for curated protein sequences.
Updated On: Jul 31, 2026
- GenBank
- EMBL
- DDBJ
- SWISS-PROT
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The Correct Option is D
Solution and Explanation
Step 1: Understanding the Concept:
Bioinformatics databases are organized according to the specific type of biological macromolecule sequence data they host.
Primary databases are broadly split into nucleotide sequence databases and protein sequence databases.
Step 2: Detailed Explanation:
GenBank is maintained by the National Center for Biotechnology Information (NCBI) and is a primary repository for nucleotide sequences.
EMBL (European Molecular Biology Laboratory) nucleotide database is maintained by the European Bioinformatics Institute (EBI) and stores genomic data.
DDBJ (DNA Data Bank of Japan) is the primary repository for DNA and RNA sequence data in Japan.
These three organizations form the International Nucleotide Sequence Database Collaboration (INSDC), sharing data daily.
SWISS-PROT is a highly curated, non-redundant protein sequence database containing detailed functional annotation.
It documents amino acid sequences, active sites, domain structures, and post-translational modifications.
Because SWISS-PROT is dedicated exclusively to protein and polypeptide sequence data, it does not store nucleic acid data.
Step 3: Final Answer:
Hence, the correct option is (D).
Bioinformatics databases are organized according to the specific type of biological macromolecule sequence data they host.
Primary databases are broadly split into nucleotide sequence databases and protein sequence databases.
Step 2: Detailed Explanation:
GenBank is maintained by the National Center for Biotechnology Information (NCBI) and is a primary repository for nucleotide sequences.
EMBL (European Molecular Biology Laboratory) nucleotide database is maintained by the European Bioinformatics Institute (EBI) and stores genomic data.
DDBJ (DNA Data Bank of Japan) is the primary repository for DNA and RNA sequence data in Japan.
These three organizations form the International Nucleotide Sequence Database Collaboration (INSDC), sharing data daily.
SWISS-PROT is a highly curated, non-redundant protein sequence database containing detailed functional annotation.
It documents amino acid sequences, active sites, domain structures, and post-translational modifications.
Because SWISS-PROT is dedicated exclusively to protein and polypeptide sequence data, it does not store nucleic acid data.
Step 3: Final Answer:
Hence, the correct option is (D).
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