Question:

Which of the following are the modified smooth muscles of the afferent arteriole?

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Afferent arteriole → Juxtaglomerular cells → Renin secretion.
Updated On: Jul 18, 2026
  • Juxtaglomerular cells
  • Vasa recta
  • Glomerulus
  • Peritubular network
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The Correct Option is A

Solution and Explanation

Step 1: Understanding nephron structure.
The nephron is the functional unit of kidney. It includes structures involved in filtration and regulation of blood pressure and filtration rate.

Step 2: Afferent arteriole specialization.
The wall of the afferent arteriole contains specialized smooth muscle cells. These cells are modified to perform endocrine function.

Step 3: Juxtaglomerular cells.
Juxtaglomerular (JG) cells are modified smooth muscle cells present in the afferent arteriole. They secrete renin, which regulates blood pressure.

Step 4: Function of renin secretion.
Renin activates the renin-angiotensin system, controlling glomerular filtration rate and systemic blood pressure.

Step 5: Evaluation of other options.
Vasa recta and peritubular networks are capillary structures, while glomerulus is a filtration unit, not modified smooth muscle.

Step 6: Final conclusion.
Thus, juxtaglomerular cells are modified smooth muscles of the afferent arteriole.
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