Question

Which immunoglobulin class is primarily involved in mucosal immunity?

• A. IgG
• B. IgA
• C. IgM
• D. IgE

Hint:

{IgA = Mucosal Antibody}.
Found in saliva, tears, mucus, and breast milk.

Answer 1

The Correct Option is B

Concept: Immunoglobulins (antibodies) are proteins produced by plasma cells that play a crucial role in the immune response. Different classes of immunoglobulins have distinct functions in the body.
Step 1:Understanding mucosal immunity.
Mucosal surfaces such as the respiratory tract, gastrointestinal tract, and urogenital tract are constantly exposed to pathogens. Specialized immune mechanisms protect these surfaces.
Step 2:Role of IgA.
Immunoglobulin A (IgA) is the primary antibody found in mucosal secretions including:

• Saliva
• Tears
• Breast milk
• Intestinal secretions

Step 3:Function of IgA.
IgA prevents pathogens from attaching to mucosal epithelial cells and neutralizes toxins and viruses before they enter tissues. Thus, the immunoglobulin primarily responsible for mucosal immunity is IgA.