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which gene is associated with autosomal dominant
Question:
Which gene is associated with autosomal dominant Parkinsonism?
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LRRK2 mutation → most common cause of inherited (autosomal dominant) Parkinson’s disease.
TS PGECET - 2024
TS PGECET
Updated On:
May 22, 2025
UCHL1
LRRK2
TIMP2
UCHL3
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The Correct Option is
B
Solution and Explanation
Mutations in the LRRK2 gene (Leucine-rich repeat kinase 2) are known to cause autosomal dominant forms of Parkinson's disease. It is the most common genetic cause of familial Parkinsonism and also occurs in sporadic cases.
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