Question

Which gene is associated with autosomal dominant Parkinsonism?

• A. UCHL1
• B. LRRK2
• C. TIMP2
• D. UCHL3

Hint:

LRRK2 mutation → most common cause of inherited (autosomal dominant) Parkinson’s disease.

Answer 1

The Correct Option is B

Mutations in the LRRK2 gene (Leucine-rich repeat kinase 2) are known to cause autosomal dominant forms of Parkinson's disease. It is the most common genetic cause of familial Parkinsonism and also occurs in sporadic cases.