Question:
Which covalent bond is present in nucleic acid?
Which covalent bond is present in nucleic acid?
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Peptide bonds are for proteins; phosphodiester bonds are specific to nucleic acids.
Updated On: Jul 2, 2026
- Peptide bond
- Phosphodiester bond
- Glycosidic bond
- Thymine bond
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The Correct Option is B
Approach Solution - 1
Phosphodiester bonds link the 3’ carbon atom of one sugar molecule to the 5’ carbon atom of another sugar in DNA and RNA backbones. These bonds are essential for nucleic acid structure.
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Approach Solution -2
Elimination approach:
Peptide bonds join amino acids in proteins, not nucleotides, so this is unrelated to nucleic acid structure. "Thymine bond" is not a recognised chemical bond type at all, it is a distractor. Glycosidic bonds do occur in nucleic acids (linking base to sugar) but they are not what physically holds the polynucleotide chain together. The backbone of DNA and RNA is built by repeatedly joining the 3' hydroxyl of one sugar to the 5' phosphate of the next via an ester linkage on each side of the phosphate group, i.e. a phosphodiester bond, making it the defining covalent linkage of the nucleic acid backbone.
Peptide bonds join amino acids in proteins, not nucleotides, so this is unrelated to nucleic acid structure. "Thymine bond" is not a recognised chemical bond type at all, it is a distractor. Glycosidic bonds do occur in nucleic acids (linking base to sugar) but they are not what physically holds the polynucleotide chain together. The backbone of DNA and RNA is built by repeatedly joining the 3' hydroxyl of one sugar to the 5' phosphate of the next via an ester linkage on each side of the phosphate group, i.e. a phosphodiester bond, making it the defining covalent linkage of the nucleic acid backbone.
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