Question:

Which bonds hold together the two complementary polynucleotide chains of DNA?

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DNA bonding rule: Backbone = phosphodiester, Between strands = hydrogen bonds.
Updated On: May 4, 2026
  • Peptide
  • Phosphodiester
  • Glycosidic
  • Hydrogen
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The Correct Option is D

Solution and Explanation

Concept:
DNA consists of two antiparallel polynucleotide chains held together by specific bonds between nitrogenous bases.

Step 1:
Understand bonding in DNA.
• Hydrogen bonds → Between complementary bases (A-T, G-C)
• Phosphodiester bonds → Within a single strand
• Glycosidic bonds → Between sugar and base

Step 2:
Identify correct bond. The two strands of DNA are held together by hydrogen bonds between base pairs. \[ A-T \rightarrow 2 \text{ hydrogen bonds}, \quad G-C \rightarrow 3 \text{ hydrogen bonds} \]

Step 3:
Analyze options.
• (A) Peptide → Protein bond $\times$
• (B) Phosphodiester → Within strand $\times$
• (C) Glycosidic → Base-sugar bond $\times$
• (D) Hydrogen → Between strands \checkmark

Step 4:
Conclusion. \[ \text{DNA strands are held together by hydrogen bonds} \]
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