Question

Which among the following is not the process of drug degradation:

• A. Photolysis
• B. Decarboxylation
• C. Hemolysis
• D. Hydrolysis

Hint:

Drug degradation occurs via processes like hydrolysis, oxidation, photolysis, and decarboxylation. Hemolysis is unrelated as it involves the destruction of red blood cells.

Answer 1

The Correct Option is C

Step 1: Understanding drug degradation processes. Drug degradation refers to the chemical breakdown of pharmaceutical compounds, leading to loss of potency and stability. The major processes of drug degradation include: 
- Photolysis: Breakdown of a drug due to exposure to light. - Decarboxylation: Loss of a carboxyl group (\(-COOH\)), leading to structural modifications. 
- Hydrolysis: Reaction with water causing drug decomposition, common in esters and amides. 

Step 2: Why hemolysis is incorrect. - Hemolysis refers to the breakdown of red blood cells (RBCs), releasing hemoglobin into the blood. It is a biological process, not related to drug degradation. 

Step 3: Explanation of incorrect options. - (A) Photolysis, (B) Decarboxylation, and (D) Hydrolysis are all valid mechanisms of drug degradation.