Question:
What is the function of IL-1?
What is the function of IL-1?
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This macrophage cytokine resets the hypothalamic thermostat to cause fever.
Updated On: Jun 23, 2026
- Enhances hematopoiesis
- Stimulates mast cells
- Has antiviral properties
- Endogenous pyrogen
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The Correct Option is D
Solution and Explanation
Step 1: Interleukin-1 (IL-1), formerly called lymphocyte-activating factor (LAF), is a key proinflammatory cytokine produced mainly by macrophages. Step 2: Its hallmark action is acting as an endogenous pyrogen; it resets the hypothalamic thermostat to produce fever, augments T-cell activity, and induces acute-phase reactants. Step 3: Antiviral activity is the role of interferons, not IL-1, so that option is wrong. Step 4: Among the options, IL-1 functioning as an endogenous pyrogen is the correct and most characteristic answer.
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