Step 1: Identifying trigonometric identities.
We are given the expression:
\[
\tan 20^\circ \cdot \tan 80^\circ \cdot \cot 50^\circ.
\]
We know the following trigonometric identities:
\[
\tan(90^\circ - x) = \cot x.
\]
This identity tells us that:
\[
\tan 80^\circ = \cot 10^\circ.
\]
Thus, we can rewrite the expression as:
\[
\tan 20^\circ \cdot \cot 10^\circ \cdot \cot 50^\circ.
\]
Step 2: Simplifying using complementary angles.
Next, we know that:
\[
\cot(90^\circ - x) = \tan x.
\]
Using this identity, we can simplify \( \cot 50^\circ \) as:
\[
\cot 50^\circ = \tan 40^\circ.
\]
Substitute this into the expression:
\[
\tan 20^\circ \cdot \tan 40^\circ \cdot \cot 50^\circ = \tan 20^\circ \cdot \tan 40^\circ.
\]
Step 3: Using the tangent addition formula.
We use the following identity for the tangent of the sum of two angles:
\[
\tan(A + B) = \frac{\tan A + \tan B}{1 - \tan A \cdot \tan B}.
\]
For \( A = 20^\circ \) and \( B = 40^\circ \), we have:
\[
\tan(20^\circ + 40^\circ) = \frac{\tan 20^\circ + \tan 40^\circ}{1 - \tan 20^\circ \cdot \tan 40^\circ} = \tan 60^\circ.
\]
We know that \( \tan 60^\circ = \sqrt{3} \), so:
\[
\tan 20^\circ \cdot \tan 40^\circ = \sqrt{3}.
\]
Step 4: Conclusion.
The given expression simplifies to:
\[
\tan 20^\circ \cdot \tan 80^\circ \cdot \cot 50^\circ = 2 \sqrt{3}.
\]
Thus, the correct answer is:
\[
\boxed{2 \sqrt{3}}.
\]