Step 1: Identify a point on the line and its direction vector.
The given line is
\[
\frac{x-4}{-2}=\frac{y-4}{2}=\frac{z-6}{1}
\]
Comparing with the symmetric form
\[
\frac{x-x_1}{a}=\frac{y-y_1}{b}=\frac{z-z_1}{c}
\]
we get a point on the line as
\[
A=(4,4,6)
\]
and the direction vector of the line as
\[
\vec{d}=(-2,2,1)
\]
Step 2: Write the coordinates of the given external point.
The given point is
\[
P=(2,3,4)
\]
We now form the vector from the point on the line \( A \) to the external point \( P \):
\[
\overrightarrow{AP}=P-A=(2-4,\ 3-4,\ 4-6)
\]
\[
\overrightarrow{AP}=(-2,-1,-2)
\]
Step 3: Recall the formula for shortest distance from a point to a line in 3D.
If \( \vec{r} \) is the vector from a point on the line to the given point, and \( \vec{d} \) is the direction vector of the line, then the shortest distance is
\[
\text{Distance}=\frac{|\vec{r}\times\vec{d}|}{|\vec{d}|}
\]
Here,
\[
\vec{r}=\overrightarrow{AP}=(-2,-1,-2)
\quad \text{and} \quad
\vec{d}=(-2,2,1)
\]
Step 4: Find the cross product \( \overrightarrow{AP}\times\vec{d} \).
\[
\overrightarrow{AP}\times\vec{d}
=
\begin{vmatrix}
\hat{i} & \hat{j} & \hat{k}
-2 & -1 & -2
-2 & 2 & 1
\end{vmatrix}
\]
Expanding,
\[
= \hat{i}\bigl((-1)(1)-(-2)(2)\bigr)
-\hat{j}\bigl((-2)(1)-(-2)(-2)\bigr)
+\hat{k}\bigl((-2)(2)-(-1)(-2)\bigr)
\]
\[
= \hat{i}(-1+4)-\hat{j}(-2-4)+\hat{k}(-4-2)
\]
\[
=3\hat{i}+6\hat{j}-6\hat{k}
\]
Step 5: Find the magnitudes needed in the formula.
Now,
\[
|\overrightarrow{AP}\times\vec{d}|=\sqrt{3^2+6^2+(-6)^2}
\]
\[
=\sqrt{9+36+36}=\sqrt{81}=9
\]
Also,
\[
|\vec{d}|=\sqrt{(-2)^2+2^2+1^2}
\]
\[
=\sqrt{4+4+1}=\sqrt{9}=3
\]
Step 6: Apply the distance formula.
Therefore,
\[
\text{Shortest distance}=\frac{|\overrightarrow{AP}\times\vec{d}|}{|\vec{d}|}
=\frac{9}{3}=3
\]
Step 7: Final conclusion.
Hence, the shortest distance between the point and the line is
\[
\boxed{3}
\]
Therefore, the correct option is
\[
\boxed{(3)\ 3}
\]