The short-acting anticholinesterase drug is:
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- Physostigmine
- Edrophonium
- Ecothiophate
- Neostigmine
The Correct Option is B
Solution and Explanation
Step 1: Understanding anticholinesterase drugs. Anticholinesterase drugs inhibit the enzyme acetylcholinesterase, thereby increasing the levels of acetylcholine in the synaptic cleft. They are classified based on their duration of action into short-acting, intermediate-acting, and long-acting drugs.
Step 2: Characteristics of Edrophonium. Edrophonium is a short-acting anticholinesterase drug with a rapid onset and brief duration of action (around 10-20 minutes). It is primarily used in the diagnosis of myasthenia gravis due to its quick effect.
Step 3: Why other options are incorrect.
- (A) Physostigmine: Intermediate-acting anticholinesterase.
- (C) Ecothiophate: Long-acting anticholinesterase, used in the treatment of glaucoma.
- (D) Neostigmine: Intermediate-acting anticholinesterase, used in the treatment of myasthenia gravis and to reverse neuromuscular blockade.
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