Concept:
Modern biotechnology involves deliberate manipulation of DNA using laboratory (in vitro) techniques to achieve desired traits.
Step 1: Understand the definition.
Genetic engineering refers to:
• Artificial manipulation of genetic material
• Performed outside the organism (in vitro)
• Aimed at producing desired characteristics
Step 2: Differentiate options.
• (A) Traditional biotechnology → Uses natural processes (e.g., fermentation) $\times$
• (B) Genetics → Study of heredity, not manipulation $\times$
• (C) Genetic engineering → Direct manipulation of DNA \checkmark
• (D) PCR → Technique for DNA amplification, not overall manipulation $\times$
Step 3: Conclusion.
\[
\text{Manipulation of genetic material in vitro = Genetic engineering}
\]